Every episode of The Journal., briefed the morning after, with up to nine more shows in one daily email.
Free for 30 days. No card needed. $4.99 a month after.
The Cancer Vaccine That Could Save Moderna
What was discussed
Moderna's financial decline post-COVID0:14
- Xavier Martinezassertion
Moderna's stock dropped over 90% from its peak and the company was bleeding cash.
Moderna melanoma vaccine clinical results1:13
- Xavier Martinezopinion
The vaccine results could be one of the biggest advancements in cancer in the last 25 years.
Moderna's mRNA platform technology3:41
- Xavier Martinezassertion
mRNA acts as a temporary instruction manual that shuttles directions from DNA to different parts of the body.
Moderna's early avoidance of oncology5:16
- Stephane Bancelassertion
Picking the wrong biology could make people blame the mRNA technology instead of the disease target.
Stephen Hoge's push for cancer research6:47
- Xavier Martinezassertion
Stephen Hoge was the dreamer and scientist who believed in turning medicine into information.
Hedge fund investor's cancer vaccine funding9:09
- Xavier Martinezassertion
A hedge fund manager sent a $500,000 check that launched Moderna's oncology program.
Moderna and Merck cancer vaccine partnership12:17
- Xavier Martinezassertion
Merck agreed to pay $200 million to fund the research despite initial doubts about whether it would work.
COVID-19 pandemic impact on cancer program14:32
- Xavier Martinezassertion
Moderna had to choose between treating cancer patients or making doses for the global public.
Moderna's financial windfall and subsequent cuts15:06
- Xavier Martinezassertion
Moderna generated $36 billion in COVID vaccine sales but later cut jobs and research programs.
Phase two and three melanoma vaccine trials16:53
- Xavier Martinezassertion
The phase three trial included over 1,000 high-risk melanoma patients.
Moderna's early positive vaccine results announcement19:07
- Xavier Martinezassertion
CEO Stephane Bancel declared, 'We are now an oncology company,' signaling a major strategic shift.
FDA approval and vaccine pricing uncertainty19:35
- Xavier Martinezassertion
The Trump administration has shown skepticism about mRNA technology.
- Stephane Bancelassertion
The new treatment will be priced less than other cancer therapies that can cost up to $500,000.
Every episode of The Journal., briefed the morning after, with up to nine more shows in one daily email.
Free for 30 days. No card needed. $4.99 a month after.
More from The Journal.
Automated summaries of what was said on each show — not claims by DailyDossier and not independently verified.